Scientists Unravel Life-saving Effect of Dexamethasone in COVID-19

New approach for targeted drug development

05-Jul-2024 - Dexamethasone is one of the most important drugs in the treatment of severe COVID-19, but patients respond very differently to the therapy. Researchers at the DZNE and Charité – Universitätsmedizin Berlin have now discovered how the cortisone compound influences the impaired inflammatory response ...

The fatal role of T cells in COVID-19

Safety mechanism is put out of action

06-Jan-2022 - Scientists from the Berlin Institute of Health at Charité (BIH), together with colleagues from Charité – Universitätsmedizin Berlin and the university hospitals in Bonn and Aachen, have found a type of immune cells that is particularly active in severely ill COVID-19 patients. The CD16 positive T ...

Cancer cells on the wrong path

How adaptations can make cancer treatment more difficult

01-Sep-2021 - Each tumor consists of multiple cell types, all of which have distinct characteristics. In addition to determining the course of the disease, these differences between individual cancer cells control the effectiveness of targeted therapies. A team of researchers from Charité – Universitätsmedizin ...

Strong antiviral immunity in the upper airways protects children from severe COVID-19

19-Aug-2021 - Children can also be infected with the novel coronavirus SARS-CoV-2, but have a substantially lower risk for developing severe COVID-19 disease compared to adults. A team of scientists from the Berlin Institute of Health at Charité (BIH), Charité – Universitätsmedizin Berlin, University of ...

What cells does the novel coronavirus attack?

09-Apr-2020 - Scientists from the Berlin Institute of Health (BIH), Charité – Universitätsmedizin Berlin and the Thorax Clinic at Heidelberg University Hospital, whose collaboration is taking place under the auspices of the German Center for Lung Research (DZL), have examined samples from non-virus infected ...