Cancer - 26 News by MDC

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Cancer - 26 News by MDC

Tip: You can further refine your news selection by departments and industries.

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Multiple myeloma: When cancer cells break out of the bone marrow, a dangerous diversity arises

The findings could be crucial for the further development of diagnostics and therapy

12-Feb-2025 - A research team from the Heidelberg Medical Faculty, the German Cancer Research Center (DKFZ), the Berlin Institute of Health at Charité (BIH) and the Max Delbrück Center has discovered new details about the spread of the incurable bone marrow cancer multiple myeloma in the body: When the cancer ...

cancer bone marrow bone marrow cancer
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Captain T Cell secures seed financing round

Start-up develops first-in-class efficacy-enhanced TCR-T cells for solid tumors that are not addressed by existing therapies

28-May-2024 - Captain T Cell, a spin-off from the Max Delbrück Center, raised €8.5 million in startup funding. The startup focuses on developing T cells to target solid tumors. The funds are intended to move a new generation of T cell therapies towards the clinic. Captain T Cell GmbH announced the successful ...

cancer cell therapies seed financing
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Computer-engineered DNA to study cell identities

“We can follow with our eyes the color in a petri dish when we give a treatment”

12-Feb-2024 - A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. Reported by the Gargiulo lab in “Nature Communications”, it will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based ...

cancer artificial DNA cells
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Zebrafish “avatars” to help tailor glioblastoma therapies

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma

09-Oct-2023 - Glioblastoma is an aggressive and difficult-to-treat brain tumor in adults. On average, patients survive for only 1.5 years. The standard of care treatment for this disease, which includes surgery followed by radiation and chemotherapy, has not changed in 18 years. That’s partly because the ...

cancer brain tumors fluorescence microscopy
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Starting up with highly promising immunotherapies

Fighting cancer with specially equipped T cells

04-Oct-2023 - After spending many years researching together, a group of scientists has founded CARTemis Therapeutics, a spin-off from the Max Delbrück Center. Uta Höpken, Armin Rehm, Anthea Wirges, and Mario Bunse want to use novel CAR T-cell therapies to help patients with cancers that are currently ...

cancer blood cancer bone marrow cancer
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How cells rewrite their fate

The study could be the starting point for new methods to alter the molecular mechanisms of cancer development

07-Jul-2023 - An international research team, including Achim Leutz of the Max Delbrück Center, has discovered that a specific protein controls the conversion of immune cells. If it were possible to intervene in this process, the development of cancer could be prevented. Cell fate determines which cell type a ...

cancer B-lymphocytes cells
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How cancer genes become independent

Study sheds light on the mysterious evolution of DNA rings

09-May-2023 - Tumors sometimes seem to take on a life of their own, growing at an unusually fast rate or suddenly developing resistance to a cancer drug. This behavior is often explained by cancer genes separating from the cell’s own chromosomes and “striking out on their own” in ring shapes. So far, little ...

cancer neuroblastoma
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AI analysis of cancer mutations may improve therapy

"A single test tells us something about the cellular mechanisms involved in cancer formation"

27-Jan-2023 - Combining single-cell data with a self-learning algorithm reveals how structural changes in chromosomes can trigger cancer. This new method could pave the way for personalized cancer treatments, writes a team led by Ashley Sanders in “Nature Biotechnology”. Cancer has many faces – no wonder, ...

cancer chromosomes gene expression
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Keeping aggressive cancer cells in check

An astonishing observation

23-Sep-2022 - BRCA1/2-mutated tumor cells often survive treatment, whether it’s chemo- or radiotherapy, because they can repair therapy-induced DNA damage. A team led by Claus Scheidereit of the Max Delbrück Center has now reported in The EMBO Journal how blocking the TSG101 protein hinders these tumor cells ...

cancer apoptosis breast cancer
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Unstoppable against blood cancer

What was previously only possible in the mouse model, the researchers now show in human cells

26-Jul-2022 - For people with certain forms of leukemia, lymphoma or multiple myeloma, they are sometimes the last chance to beat the cancer: Treatments with chimeric antigen receptor T cells, or CAR T cells for short. For this purpose, T cells are taken from the patient's blood to equip them with artificially ...

cancer blood cancer cancer cells
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