New imaging analysis method revolutionizes the diagnosis of head and neck tumors

01-Nov-2024 - Head and neck cancers are among the ten most common cancers worldwide. Head and neck tumors account for about 3-5% of all cancers, with squamous cell carcinomas being the predominant form. They occur in areas such as the oral cavity, pharynx and larynx. An international team of researchers led by ...

A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA

Researchers present the PUMA technology for the precise detection of RNA with DNA-cutting Cas12 nucleases

18-Jul-2024 - CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg have expanded this extensive toolbox. Their novel method, called PUMA, enables the ...

Faster neuroborreliosis diagnosis using biomarkers

Clear threshold value of the cellular messenger substance CXCL13 allows diagnosis of neuroborreliosis to be improved

11-Jul-2024 - A newly defined threshold for the concentration of the cytokine CXCL13 may improve the diagnosis of neuroborreliosis. The clinical diagnosis of this disease, which is caused by infections from tick bites, is still difficult and often occurs long after infection. CXCL13 now makes it possible to ...

AI model finds the cancer clues at lightning speed

Say goodbye to hours, even days, of detective work

08-Jul-2024 - Researchers at the University of Gothenburg have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than the current semi-manual method. Glycans, or structures of sugar molecules in our cells, ...

New disease discovered: How the immune system destroys the cerebellum

Study identifies new autoantibodies in cerebrospinal fluid as a possible biomarker for rapidly progressing cerebellitis

03-Jun-2024 - Cerebellar ataxia is a neurological disorder of the cerebellum. This important area at the back of the brain acts as a conductor, so to speak, coordinating our movements and keeping us in balance. This ability is impaired in cerebellar ataxia. Affected people can have difficulties walking, ...

PharmaKure announces collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

New collaboration will enhance ability to identify those more at risk of developing brain diseases to enable earlier interventions

04-Mar-2024 - PharmaKure announces a new epigenetics collaboration with Sheffield Hallam University. This partnership will focus on ‘gene-based environmental biomarkers’, known as epigenetic markers, for calculating risk scores for Alzheimer’s diseases. Together withALZmetrixTM, PharmaKure’s blood-based ...

Lighting up Alzheimer’s-related proteins to allow for earlier disease detection

08-Feb-2024 - Many neurodegenerative diseases, including Alzheimer’s and Parkinson’s, are difficult to diagnose before symptoms begin to appear. However, disease-related biomarkers such as aggregated proteins called amyloids could provide important insight much earlier, if they can be readily detected. ...

Enabling early detection of cancer: AI helps

Blood cells reveal tumours in the body: Researchers achieve an advance with the development of a test for early diagnosis of cancer

18-Dec-2023 - The ability to detect a developing tumour at a very early stage and to closely monitor the success or failure of cancer therapy is crucial for a patient’s survival. A breakthrough on both counts has now been achieved by researchers at the Paul Scherrer Institute PSI. Researchers led by G.V. ...

A sugar analysis could reveal different types of cancer

In the future, a little saliva may be enough to detect an incipient cancer

15-Dec-2023 - Researchers at the University of Gothenburg have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells. Glycans are a type of sugar molecule structures that is linked to the proteins in our cells. The structure of the glycan determines the function of ...

Risk of serious COVID-19 infection can now be predicted

Researchers develop rapid test for severe infections

30-Nov-2023 - Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe COVID-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a COVID-19 ...