Biology - 3 News from the science department by RUB from Germany for the biotechnology industry

Biology - 3 News from the science department by RUB from Germany for the biotechnology industry

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Proteomic profiling reveals innovation potential of new antibiotics

Research team intends to use proteomics to accelerate the development of new drugs

21-Oct-2020 - The fight against bacterial infections, especially those caused by resistant pathogens, is in full swing with the search for new antibiotic agents. The aim is to identify substances that attack the pathogens in a truly novel way. The team at the Center for Systems-Based Antibiotic Research ...

biology proteomics antibiotics
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Novel optogenetic tool

Switching specific G-protein-coupled signalling pathways on and off

12-Apr-2016 - Blue on, yellow off: using different-coloured light, researchers are able to switch signalling pathways in the brain on and off. Researchers in Bochum have utilised light-sensitive proteins from nerve cells of the eye – so-called melanopsins – to switch on specific signalling pathways in brain ...

biology optogenetics brain
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“Two in One” enzyme: unusually flexible Scientists from the RUB have solved the structure of a viral protein

The Journal of Biological Chemistry has ranked this documentation as “Paper of the Week.”

09-Oct-2008 - A virus that infects the marine cyanobacterium Prochlorococcus can produce specific pigments more effectively than its host can. It requires only one enzyme, in contrast to the host Prochlorococcus, which needs two enzymes. The virus makes use of phycoerythrobilin synthase, a “two in one” enzyme. ...

biology molecular biology catalysis

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