Biology - 12 News by Rockefeller University for the healthcare industry

Tip: You can further refine your news selection by departments.

Biology - 12 News by Rockefeller University for the healthcare industry

Tip: You can further refine your news selection by departments.

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Structural studies reveal workings of a molecular pump that ejects cancer drugs

28-Feb-2017 - Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining ...

biology cell biology antibiotics
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Atomic-scale view of bacterial proteins offers path to new tuberculosis drugs

06-Feb-2017 - With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, Rockefeller scientists are suggesting strategies for new drugs to curb this growing health problem. Each year, nearly half a million people around the world are infected with ...

biology biochemistry molecular biology
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How protein production gets distorted in skin cancer

30-Jan-2017 - Each cell in the body follows a strict protocol for manufacturing the proteins it needs to function. When a cell turns cancerous, however, its protein production goes off script. A new study led by researchers at The Rockefeller University takes a close look at one way in which this procedure ...

biology cell biology cells

Antibody combination puts HIV on the ropes

27-Jan-2017 - Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body's ability to control it. But a small group of infected individuals--called elite controllers--possess immune systems capable of defeating the ...

biology immunology molecular biology
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Cancer can arise from changes in the proteins that package DNA

17-May-2016 - A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new findings from researchers at The Rockefeller University . The mutation is present in histones, the protein scaffolding around which DNA wraps. Researchers have ...

biology epigenetics chromatin
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Study links epigenetic processes to the development of the cerebellar circuitry

24-Dec-2015 - From before birth through childhood, connections form between neurons in the brain, ultimately making us who we are. So far, scientists have gained a relatively good understanding of how neural circuits become established, but they know less about the genetic control at play during this crucial ...

biology epigenetics cerebellum

New study helps explain how botulism-causing toxin can enter circulation

14-May-2010 - New research in the Journal of Cell Biology helps explain how the toxic protein responsible for botulism can enter circulation from the digestive system. Botulism, a rare but serious paralytic illness, is caused by botulinum neurotoxin (BoNT), an extremely toxic protein that is produced by the ...

biology adhesion botulism

New insight into Parkinson's disease

21-Apr-2010 - New research provides crucial insight into the pathogenic mechanisms of Parkinson's disease (PD), a prevalent neurodegenerative disorder. The study appears in the Journal of Cell Biology. The identification of inherited mutations in genes such as Parkin and PINK1 ( PTEN-induced putative kinase 1 ...

biology genes mitochondria

Defective protein is a double hit for ataxia

07-Apr-2010 - The neurodegenerative disease spinocerebellar ataxia type 5 (SCA5) damages nerve cells in two ways. University of Minnesota researchers now report that the defective protein responsible for the disease cuts the number of synaptic terminals and snarls traffic inside neurons. The study appears in ...

biology Alzheimer's disease amyotrophic lateral sclerosis

Overcoming tumor resistance to anti-cancer agent TRAIL

25-Mar-2010 - The TRAIL ligand is a promising anticancer agent that preferentially kills tumor cells without apparent damage to healthy cells. Many cancers exhibit resistance to TRAIL, however, thus limiting its therapeutic potential. According to a study in the Journal of Cell Biology, small molecules known ...

biology Expression Germany
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