Bacteria - 38 News by Helmholtz-Zentrum für Infektionsforschung

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Bacteria - 38 News by Helmholtz-Zentrum für Infektionsforschung

Tip: You can further refine your news selection by departments and industries.

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Chemical trick activates antibiotic directly at the pathogen

Click-to-release technique avoids the severely nephrotoxic effect of colistin

23-Oct-2024 - Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in around 30 percent of treated patients. A research team at the Helmholtz Centre for Infection Research (HZI) and the ...

bacteria Acinetobacter baumannii antibiotic resistance
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Drug discovery within the patient

Genetic analysis of bacteria from humans and animals paves the way for new active ingredients

21-Oct-2024 - Microorganisms do not just colonize the body of mammals during infections. Billions of microbes can be found on and in healthy humans and animals at any given time, communicating with each other via chemical signals and thus influencing their health. In two studies, researchers from the Helmholtz ...

bacteria active ingredient search genome sequencing
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New drugs from toxic birds

Investigation of the symbiosis between bacteria and birds leads to the discovery of new natural products with antimicrobial properties

10-Oct-2024 - Bacteria are a valuable source for the discovery of natural products that can be used for the development of new drugs. A HIPS research team has now identified two new classes of active substances with antimicrobial properties from bacteria that live in symbiosis with a toxic bird. This strategy ...

bacteria anti-infectives antibiotic resistance
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Unlocking the world of bacteria

Researchers introduce novel approach to DNA transformation and genetic mutation of bacteria: The basis for new antibiotics and cell-based therapies

28-Jun-2024 - Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team led by the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has ...

bacteria genetic engineering genetically modified organisms
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Searching for the microbial treasure

New family of bacteria with high pharmaceutical potential discovered

17-May-2024 - Most antibiotics used in human medicine originate from natural products derived from bacteria and other microbes. Novel microorganisms are therefore a promising source of new active compounds - also for the treatment of diseases such as cancer or viral infections. A team from the Helmholtz ...

bacteria myxobacteria active ingredient research
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New starting point discovered in the fight against Pseudomonas aeruginosa

Research team shows how an enzyme regulates the pathogenicity of a clinically relevant pathogen

18-Mar-2024 - Pseudomonas aeruginosa is an important opportunistic pathogen responsible for life-threatening infections that are associated with high rates of morbidity and mortality. Researchers from TWINCORE, the Centre for Experimental and Clinical Infection Research in Hannover, and the Helmholtz Centre ...

bacteria hospital germs Pseudomonas aeruginosa
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How machine learning, data integration and AI contribute to better strategies in the fight against pathogens

Researchers develop a new machine learning approach

15-Jan-2024 - To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers from the Würzburg Helmholtz Institute for RNA-based Infection Research and the Helmholtz AI Cooperative applied data integration ...

bacteria artificial intelligence bioinformatics
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Bacterial weapons against viral diseases

Discovery of two novel classes of natural products with activity against RNA viruses

22-Mar-2023 - The COVID-19 pandemic has dramatically demonstrated that the development of effective agents against viral pathogens is of great importance for global health. Although effective vaccines are available for many viral diseases, there is an urgent need for new and effective therapeutic treatments. ...

bacteria myxobacteria soil bacteria
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When editing bacteria with CRISPR, less is more

Research team develops approach that increases efficiency of genome editing

13-Feb-2023 - Systematically attenuating DNA targeting activity can achieve CRISPR-driven editing in bacteria, greatly boosting colony counts and even increasing the frequency of precise genome editing. This was shown in a study of the Helmholtz Institute Würzburg (HIRI) in collaboration with the Helmholtz ...

bacteria CRISPR gene scissors
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Disarming pathogens: New drug candidates to combat chronic infections

Researchers use bacterial communication as a target for new drugs

25-Jan-2023 - The pathogen Pseudomonas aeruginosa is the cause of a large number of serious infections and places a particular burden on immunocompromised patients. The increasing spread of antimicrobial resistance makes it even more difficult to combat the dreaded hospital pathogen. A research team led by Dr ...

bacteria antibiotics drug design
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