New target to treat severe autoimmune disease

04-Oct-2024 - Researchers at the University of Basel have made significant progress in understanding a rare but serious immune disease. The team has uncovered critical mechanisms involved in the cellular recycling process, thus providing novel therapeutic approaches. LRBA deficiency is a rare and severe ...

Is less sugar better for our brain?

"Our research findings suggest that lactose in particular can accelerate the neurodegeneration of our brain"

25-Sep-2024 - Elevated blood sugar levels can have a direct impact on our brain. If the blood vessels change due to sugar-related deposits, individual areas of the brain can be undersupplied, which can trigger strokes as well as dementia. Scientists at the Department of Neurology at the University Hospital ...

Casting off: Leaving autoimmune disease behind thanks to an innovative treatment

Research team makes decisive breakthrough

24-Sep-2024 - Using the motto “Lichtet den Anker und segelt der Erkrankung davon!” (“Raise anchor and leave your illness behind”), the team at Department of Medicine 3 – Rheumatology and Immunology at the Deutsches Zentrum für Immuntherapy, Uniklinikum Erlangen, FAU has discovered an innovative treatment ...

ImmunOs Therapeutics raises $11 million and further strengthens investor base

“ImmunOs Therapeutics has a very innovative approach to target myeloid checkpoints which are potentially the next major breakthrough in immuno-oncology”

24-Sep-2024 - ImmunOs Therapeutics AG, a biopharmaceutical company leveraging its unique immune system modulating HLA-based technology platform to develop first-in-class therapeutics for the treatment of cancer and autoimmune diseases, announced the closing of a Series C financing round of $11 million. The ...

Autoimmunity: immune cells escape therapy due to "exhausted" state

Researchers have succeeded in isolating and analyzing disease-causing T cells from the blood in autoimmune diseases

09-Sep-2024 - In autoimmune diseases, the immune system mistakenly attacks the body's own structures. A research team from Kiel, Lübeck and Berlin has now succeeded in analyzing certain pathogenic immune cells more precisely using a method they developed. They discovered that these cells can sometimes switch ...

Impressive results against autoimmune disease

Severe systemic lupus no longer detectable after cancer medication treatment

06-Sep-2024 - The team at Charité – Universitätsmedizin Berlin is astounded by the huge improvement seen in a female patient with severe systemic lupus erythematosus (SLE) after being treated with the cancer medication teclistamab. Not long ago, the 23-year-old was wheelchair-bound due to the autoimmune ...

SciRhom Secures EUR 63 Million Series A Financing Round to Accelerate iRhom2-targeting Therapies in Autoimmune Diseases

Novel and potentially groundbreaking therapeutic strategy

10-Jul-2024 - SciRhom GmbH announced the closing of a EUR 63 million (USD 70 million) Series A financing round. The round was co-led by Andera Partners, Kurma Partners, Hadean Ventures, MIG Capital, and Wellington Partners, with participation from new investor Bayern Kapital and existing investors including ...

Millions in funding to revolutionize immunotherapy

Swiss start-up NXI Therapeutics extends pre-seed financing to CHF 3.5 million in run-up to larger seed financing

25-Jun-2024 - NXI Therapeutics AG, developer of tomorrow’s disruptive immunotherapies by coronin 1 modulation, announces the extension of a pre-Seed financing totalling to 3.5 million CHF. This financing extension comes in the run-up to a larger Seed financing that the company is currently raising. Kickfund ...

Molecular switch for the gradual reprogramming of immune cells decoded

19-Jun-2024 - The immune system activates certain white blood cells, the T helper cells (Th cells), to defend against pathogens and cancer. These cells are imprinted differently depending on the target (viruses, bacteria, parasites, tumor cells) and can promote or attenuate inflammatory reactions. A research ...

How a “date” between immune cells makes rheumatism disappear

Major success: New approach for treating autoimmune diseases

06-May-2024 - Dates don’t always work out the way you would like. This is the premise on which scientists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have developed a new approach towards treating autoimmune diseases. They brought two types of immune cells, B cells and T cells, together at one ...