How the body switches out of “fight” mode

Study unlocks how cortisone inhibits inflammation

12-Apr-2024 - Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. A team of researchers from Charité – Universitätsmedizin Berlin and Uniklinikum Erlangen have now explored the ...

Coffee with milk may have an anti-inflammatory effect

A combination of proteins and antioxidants doubles the anti-inflammatory properties in immune cells

03-Feb-2023 - Can something as simple as a cup of coffee with milk have an anti-inflammatory effect in humans? Apparently so, according to a new study from the University of Copenhagen. A combination of proteins and antioxidants doubles the anti-inflammatory properties in immune cells. The researchers hope to ...

Frankincense reprograms inflammatory enzyme

Change of direction in immune defence

13-May-2020 - A research team from the University of Jena and Louisiana State University (USA) has clarified the molecular mechanism behind the anti-inflammatory effect of a natural product from frankincense resin. The enzyme 5-lipoxygenase plays a key role here: the natural product reprograms the normally ...

Promising transport molecule for steroid medications discovered

09-Nov-2016 - When the word steroids comes up, a lot of people think of doping. It is much less well known that steroids are used in the treatment of many diseases, such as asthma, neurodermatitis, multiple sclerosis, and Crohn’s Disease. Scientists at the Karlsruhe Institute of Technology (KIT) and Jacobs ...

Scientists show commonly prescribed painkiller slows cancer growth

27-May-2016 - Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types ...

Anti-inflammatory drugs may improve survival from severe malaria

25-May-2012 - A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage.Walter and Eliza Hall Institute researchers have shown that a new class of anti-inflammatory agents, called IDR ...

UF study strengthens concerns about long-term use of certain painkillers

26-Jul-2011 - Painkillers such as ibuprofen, naxopren and celecoxib provide needed relief for many patients who have chronic pain. But an ongoing source of contention is whether those drugs and others in their class known as nonsteroidal anti-inflammatory drugs, or NSAIDs, are linked to harmful health ...

Rheumatoid arthritis signaling protein reverses Alzheimer's disease in mouse model

New study shows GM-CSF reduces AD pathology and eliminates memory loss

24-Aug-2010 - A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer's disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports. Researchers found that the ...

Anti-inflammatory drugs can help block hypertension-related kidney damage

17-May-2010 - Anti-inflammatory drugs appear to help block the rapid kidney destruction that can occur with hypertension, Medical College of Georgia researchers report. Treating hypertensive rats with the broad-acting anti-inflammatory drug pentosan polysulfate preserves the kidney's ability to regulate ...

Regular Analgesic Use Increases Hearing Loss in Men

02-Mar-2010 - In a study published in The American Journal of Medicine, researchers determined that regular use of aspirin, acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk of hearing loss in men, particularly in younger men, below age 60. Investigators from Harvard ...