A key to analyzing millions of individual cells

Artificial intelligence in biomedicine

27-Jan-2025 - Our bodies are made up of around 75 billion cells. But what function does each individual cell perform and how greatly do a healthy person’s cells differ from those of someone with a disease? To draw conclusions, enormous quantities of data must be analyzed and interpreted. For this purpose, ...

A New Open-Source Tool for Analyzing Complex Health Data

Sort, group, and analyze large, heterogeneous, and complex datasets without any pre-existing hypotheses

13-Sep-2024 - Led by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for the analysis of complex medical health data. The open-source software called “ehrapy” enables researchers to structure and systematically examine large, heterogeneous datasets. The ...

Interpreting Large-Scale Medical Datasets

ScPoli Enables Multi-Scale Representations of Cells and Samples

10-Oct-2023 - The increasing amount of data recorded in medical research can only lead to scientific breakthroughs and essential therapies for patients if interpreted and analyzed correctly. Computer scientists at Helmholtz Munich developed a generative model named scPoli (single-cell population level ...

Looking at the good vibes of molecules: a new method for label-free metabolic imaging

09-Jan-2020 - Label-free dynamic detection of biomolecules is a major challenge in live-cell microscopy. The simultaneous visualization of dynamic alterations for classes of metabolites, such as carbohydrates and lipids, was an unmet need in biomedical research. Now, a novel imaging method developed by a ...

New algorithm detects even the smallest cancer metastases across the entire mouse body

Exposing the enemy

16-Dec-2019 - Teams at Helmholtz Zentrum München, LMU Munich and the Technical University of Munich (TUM) have developed a new algorithm that enables automated detection of metastases at the level of single disseminated cancer cells in whole mice. Cancer is one of the leading causes of death worldwide. More ...

Cell atlas of the aging lung

01-Mar-2019 - Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. In order to understand these effects in detail, researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), analyzed the aging process in the lung at ...

Big Data for small cells – a new tracking and quantification tool for single cells

20-Jul-2016 - Working with colleagues from the ETH Zürich, scientists at the Helmholtz Zentrum München and the Technical University of Munich have developed software that allows observing cells for weeks while also measuring molecular properties. Certain questions in modern cell biology can only be answered by ...

Important clue to understanding the pathogenesis of ciliary disorders

26-Jul-2010 - Scientists led by Dr. Heiko Lickert, research group leader at the Institute of Stem Cell Research of Helmholtz Zentrum München, have identified the first gene shown to regulate cilia disassembly in a living organism. If the gene is defective, double and forked cilia develop – thus the name ...