US PTO granting Probiodrug a Further Medical Use Patent for the Inhibition of the Enzyme Glutaminyl Cyclase (QC)
Probiodrug AG announced that the United States Patent Office issued to Probiodrug the US patent no. 7,462,599 covering compounds and methods for the inhibition of the conversion of substrates of the enzyme glutaminyl cyclase (QC), which are causative for Familial Alzheimer's diseases, such as Familial British and Familial Danish dementia.
“This patent expands our patent estate around QC inhibition as a novel treatment paradigm in Alzheimer’s disease and other CNS diseases”, said Hans-Ulrich Demuth, CSO and co-founder of Probiodrug. "Already in June, we were granted patent no. US 7,381,537, the world‘s first patent covering broad methods to treat sporadic Alzheimer’s disease using QC inhibitors."
Familial Alzheimer's disease is an uncommon form of Alzheimer's, accounting for less than 5% of all Alzheimer's sufferers, and, in many cases, is inherited. Onset of the disease usually is very early and can appear as early as 16 years of age. In contrast, sporadic Alzheimer's disease usually occurs at age 65 or beyond.
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