AdvanDx, Inc. Launches First LNA-Based In Vitro Diagnostic Test for Detection of Antibiotic Resistant 'Superbugs'
According to the company, vanA/B EVIGENE combines the high specificity of Locked Nucleic Acid (LNA) probes with EVIGENE, a signal amplified sandwich hybridization assay platform, to rapidly and accurately detect both the vanA and vanB genes that confer vancomycin resistance in enterococci and Staphylococcus aureus. A study published by the Centers for Disease Control and Prevention in the Journal of Clinical Microbiology concluded that the EVIGENE technology demonstrated 100% sensitivity and specificity for the detection of vanA in S. aureus (VRSA) and vanA or vanB in enterococci (VRE).
"We are extremely excited to see AdvanDx introduce the first LNA-based in vitro diagnostic test. This marks the transition of LNA from a research tool to a clinical diagnostic tool," said Dr. Henrik Stender, Vice President for Research and Development, at AdvanDx.
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