Urine analysis enables cardiovascular risk assessment
Researchers of mosaiques diagnostics, the British Heart Foundation (Glasgow, UK), and Baker Heart Research Institute (Melbourne, Australia) examined a total of 370 patients in an international blinded clinical study. The consortium established a diagnostic urine test distinguishing between presence and absence of CAD with sensitivity of 98% and specificity of 83%. Mosaiques' proprietary CE-MS technology (capillary electrophoresis coupled to mass spectrometry) enabled not only the successful identification of CAD patients, but also suggests the possibility of monitoring the effects of therapeutic interventions. This non invasive and precise diagnostic procedure provides tremendous benefits for patients with significantly increased risk of cardiovascular complications, such as patients with type II diabetes and the elderly in personalized medicine. According to the company, the technology already proved high advancement and impact on drug evaluation during clinical trials by a detailed assessment of drug effects on the vascular and - considering mosaiques' further diagnostics - renal architecture.
Original publication: "Urinary proteomic biomarkers in coronary artery disease."; Molecular & Cellular Proteomics 2007.
Most read news
Topics
Organizations
Other news from the department research and development
Get the life science industry in your inbox
From now on, don't miss a thing: Our newsletter for biotechnology, pharma and life sciences brings you up to date every Tuesday and Thursday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.
Most read news
More news from our other portals
See the theme worlds for related content
Topic world Diagnostics
Diagnostics is at the heart of modern medicine and forms a crucial interface between research and patient care in the biotech and pharmaceutical industries. It not only enables early detection and monitoring of disease, but also plays a central role in individualized medicine by enabling targeted therapies based on an individual's genetic and molecular signature.
Topic world Diagnostics
Diagnostics is at the heart of modern medicine and forms a crucial interface between research and patient care in the biotech and pharmaceutical industries. It not only enables early detection and monitoring of disease, but also plays a central role in individualized medicine by enabling targeted therapies based on an individual's genetic and molecular signature.
Topic World Mass Spectrometry
Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!
Topic World Mass Spectrometry
Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!