ARIUS announces allowance of US patent for lead anti-cancer antibody
The ARH460-16-2 antibody drug is in development by ARIUS for breast, prostate and liver cancers. The CD44 antigen that is targeted by this antibody has been identified as a cancer stem cell marker in several different malignancies. The discovery of cancer stem cells and the markers that distinguish this population of cancer cells from others represent a key advancement in the understanding of cancer. Such insights can be used to develop drugs, such as ARH460-16-2, to prevent the spread of cancer and extend survival in cancer patients. Recently ARIUS has also announced the initiation of a toxicology program in preparation for human clinical trials.
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