SAFC Completes Construction of Major New Protein Purification Facility

27-Apr-2007

SAFC, a member of the Sigma-Aldrich Group, has announced the construction completion of two major new protein API facilities at its St. Louis, Missouri manufacturing campus.

A new Biologics manufacturing facility consists of a 25,000 sq. ft. cGMP purification and manufacturing suite for transgenic plant and other non-animal derived protein APIs and a 6,000 sq. ft. facility for purification of animal-derived protein APIs. Validation for commercial operation of this $16 million expansion at the 400,000 sq. ft. St Louis manufacturing campus is expected by mid-year 2007.

The Biologics facility features some of the largest extraction and purification suites of their kind in the industry. The Class 100,000 (ISO 8) and Class 10,000 (ISO 7) clean rooms will accommodate multiple one-meter chromatography columns and ultrafiltration operations, with API target quantities in the five-kilogram range. Also featured is a Class 10,000 (ISO 7) lyophilization suite.

Completely separated to prevent potential cross-contamination, the facility for animal-derived API purification also features Class 100,000 (ISO 8) and Class 10,000 (ISO 7) clean rooms. These will also include multiple one-meter chromatography columns and ultrafiltration operations to give API quantities in the five-kilogram range.

Other news from the department manufacturing

These products might interest you

YMC HT Glassäulen New

YMC HT Glassäulen by YMC

YMC HT Glass Columns

Pack your own MPLC glass columns, ideal for temperature sensitive applications

chromatography columns
Superdex™ 75 Increase, Superdex 200 Increase, Superose™ 6 Increase

Superdex™ 75 Increase, Superdex 200 Increase, Superose™ 6 Increase by Cytiva

Fundamentals of size-exclusion chromatography

Your guide to SEC chromatography

chromatography systems
YMC-SEC MAB , YMC-Pack Diol

YMC-SEC MAB , YMC-Pack Diol by YMC

Efficient size exclusion chromatography with YMC-SEC MAB

Analysis of antibodies and aggregates with high stability

UHPLC columns
YMC Pilot Glass Columns

YMC Pilot Glass Columns by YMC

High-performance chromatography columns for pilot projects

Customised solutions for temperature- and chemical-sensitive separations

chromatography columns
SkillPak pre-packed columns

SkillPak pre-packed columns by Tosoh

Enhancing Bioprocessing Efficiency with Pre-packed Chromatography Columns

chromatography columns
TSKgel FCR-IIIA columns

TSKgel FCR-IIIA columns by Tosoh

Rapid Affinity Analysis of Antibodies with FcR Chromatography

affinity chromatography columns
CIMmultus®

CIMmultus® by Sartorius

Ready-to-use chromatography columns for bioseparation

High-performance monoliths for the purification of biomolecules - reusable and scalable

chromatography columns
ECOPLUS Glass Columns

ECOPLUS Glass Columns by YMC

Flexibility and precision: chromatography columns for every application

Stable under high pressure and easy to pack - for the best chromatographic results

LC columns
Prepacked ECO and ECOPLUS Columns

Prepacked ECO and ECOPLUS Columns by YMC

Individually packed chromatography columns for maximum efficiency

Packed ECO and ECOPLUS columns: Flexible solutions for IEX, AC, SEC, HIC and RP

chromatography columns
BioPro IEX

BioPro IEX by YMC

Maximum binding capacity in ion exchange chromatography

High separation performance and maximum recovery - Perfect for proteins, peptides and nucleic acids

IEX columns
ECO Glass Columns

ECO Glass Columns by YMC

Robust glass columns for demanding MPLC applications

Optimum performance with pressure limits of 5-30 bar and optional temperature control

LC columns
YMC-Triart

YMC-Triart by YMC

Efficient method development with YMC-Triart chromatography columns

Optimum performance under demanding laboratory conditions

chromatography columns
TSKgel HIC-ADC Columns

TSKgel HIC-ADC Columns by Tosoh

High-Performance HIC Columns for ADC Quality Assurance

chromatography columns
Loading...

Most read news

More news from our other portals

So close that even
molecules turn red...

See the theme worlds for related content

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

50+ products
10+ whitepaper
45+ brochures
View topic world
Topic World Chromatography

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

50+ products
10+ whitepaper
45+ brochures