JDRF To Collaborate with MediGene to Develop an Antigen-Specific Immunotherapeutic for Type I Diabetes
Type I diabetes is a disease caused by T cells that inappropriately destroy the body's own insulin-producing cells. MediGene's mTCR therapeutics engineer T cell receptors into antibody-like proteins that can be used to actively target known therapeutic compounds to target tissues. For its type I diabetes program, MediGene is developing specific mTCRs which will be used to both competitively block autoreactive T cell engagement to beta cells and to selectively target known immunosuppressive agents to the beta cell's local environment.
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