MediGene and sanofi pasteur to undertake a collaborative Research Agreement to develop high affinity monoclonal T cell receptors
MediGene will undertake the research programme using high affinity mTCRs which recognise specific HLA-peptide complexes on the surface of antigen presenting cells or tumor cells. The research has the objective of creating vaccine validation tools for sanofi pasteur by detecting these complexes.
According to the company, the monoclonal T cell receptor (mTCR) technology platform enables the production of fully human, soluble T cell receptors with picomolar affinity and exceptional selectivity. Unlike conventional therapeutic antibodies, mTCRs are ideal for targeting agents for all disease proteins; including intracellular tumour targets thereby offering a substantial advantage in the number of disease specific targets available.
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Topic world Antibodies
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