VASTox begins stem cell therapy programme with funding from the UK department for trade and industry
VASTox announced that it will begin a new proprietary drug discovery programme in the stem cell area. The new programme will be supported by grant funding from the UK Department of Trade and Industry (DTI) under the Technology Programme, which is designed to stimulate innovation in the UK economy through higher levels of research and development and knowledge transfer.
The grant will fund an 18-month £910,000 collaborative research programme entitled Understanding the Molecular Activation of Stem Cells ('UNMASC'). The aim of the programme is to screen small molecules in zebrafish and fruitflies to identify compounds that affect stem cell fate (e.g. division, proliferation and behaviour). These hits can then be developed for use in a wide range of regenerative therapies for diseases such as Crohn's disease, Parkinson's disease and cancer. The intellectual property relating to potential drugs will reside exclusively with VASTox.
VASTox will undertake the research in collaboration with academics at the University of Oxford, supported by the UK Medical Research Council: Professors Roger Patient and Tariq Enver at the Weatherall Institute of Molecular Medicine and with Dr Marcel van den Heuvel at the MRC Functional Genetics Institute. All three academics are scientific advisors to VASTox.
Under the terms of the £910,000 programme, the DTI will provide a grant of over £370,000 to VASTox, which the company will match. The remainder of the funding will support the programme's academic collaborators.
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