Affymetrix Selected to Genotype More Than 9,000 Framingham Heart Study Samples

SHARE Project to Help Identify Genetic Variants Associated With Heart, Lung, Blood and Sleep Disorders

07-Sep-2006

Affymetrix Inc. announced that it has been selected by the SHARE (SNP Health Association REsource) project for a large-scale whole-genome association study. As part of the project, Affymetrix will collaborate with the National Heart, Lung, and Blood Institute (NHLBI) and the National Center for Biotechnology Information (NCBI) of the National Institutes of Health to identify genetic variants associated with heart, lung, blood and sleep disorders.

The SHARE project will analyze more than 9,000 samples collected by the NHLBI and Boston University for the Framingham Heart Study. Clinicians have been using the Framingham Heart Study to track and measure data relating to cardiovascular disease since 1948. Data has been collected from more than 15,000 samples spanning three generations of individuals.

As part of the SHARE project, researchers will develop a data resource that will integrate genome-wide genotypic information with phenotypic information from multiple NHLBI studies. The data will be available to the scientific community for further genome-wide association analyses and will complement the data included in the recently announced Affymetrix Control Program.

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