Applied Biosystems And Genego Collaborate To Advance Understanding Of Tissue Gene Expression

08-Aug-2006

Applied Biosystems, an Applera Corporation business, and GeneGo, Inc., provider of software and databases for systems biology, announced a collaboration designed to enhance researchers' ability to study differential gene expression in biological pathways. As part of the agreement, GeneGo has integrated the Applied Biosystems Tissue Gene Expression Database into its MetaCore(TM) data mining platform.

The companies said the integration of this proprietary data into MetaCore is expected to save researchers both time and costs that would otherwise be required to generate comparable comprehensive and high-quality curated data. The combined solution facilitates microarray experiments, such as comparing gene expression changes in normal versus diseased or treated human tissues.

The Tissue Expression Database, created using the Applied Biosystems Expression Array System and Human Genome Survey Microarray, is a proprietary dataset of genome-wide gene expression values from 31 normal tissues and a Universal Human Reference RNA. This extensive dataset can serve as a baseline reference for microarray results and a source for identifying tissue-specific genes.

MetaCore is used for target selection and validation, identification of biomarkers for disease states and toxicology analysis. By enabling the visualization and analysis of complex experimental data in an integrated manner, the solution is designed for systems biology applications. MetaCore is based on a comprehensive, manually curated database of human biology, diseases, toxicology and bioactive chemistry and is designed for analysis of gene expression, genetic variations, and proteomic and metabolite profiles.

https://www.bionity.com/en/news/56890/applied-biosystems-and-genego-collaborate-to-advance-understanding-of-tissue-gene-expression.html