Celera Genomics and Medarex Establish Therapeutic Antibody Collaboration in Cancer

Collaboration Combines Celera's Protein Discoveries with Medarex's Expertise in Developing Fully Human Antibody Therapeutics

26-Jun-2006

Celera Genomics, an Applera Corporation business, and Medarex, Inc. formed a strategic collaboration to discover and develop fully human antibodies for the potential treatment of multiple cancer indications. The collaboration will encompass the development of therapeutic antibodies against proteins identified by Celera's proteomic research discovery efforts as being over-expressed on the surface of tumor cells and subsequently validated through additional research at Celera. The collaboration combines Celera's ability to discover and validate novel targets for oncology with Medarex's expertise in the development of fully human antibody therapeutics.

Under the collaboration, Celera and Medarex plan to jointly select targets from Celera's portfolio of novel cancer targets. Medarex expects to generate fully human monoclonal antibodies against these targets using its proprietary UltiMAb Human Antibody Development System®, and the two companies expect to jointly carry out initial validation studies. The two companies plan to alternate the selection of antigen-antibody research programs to further develop and commercialize the antibodies independently. The selecting party will have full development and commercialization rights to products arising from its selected research programs, and the other party will be entitled to receive milestone payments if milestones are achieved and royalties on commercial sales of any such products. The selecting company may develop antibodies generated under this collaboration internally or through external partners. Other financial terms of the agreement were not disclosed.

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Topic world Antibodies

Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous

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Topic world Antibodies

Topic world Antibodies

Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous