Viragen Reports Advancement in Avian Transgenics Biomanufacturing
Anti-cancer Antibody Expressed in Rooster
Viragen, in collaboration with Roslin Institute and Oxford Biomedica PLC, reported that an antibody designed to treat malignant melanoma (anti-GD3 antibody) has been successfully detected in the blood of a founder transgenic rooster after the antibody was introduced using a proprietary gene delivery system. This achievement is the first in a series of steps designed to confirm that a humanized antibody can be produced in subsequent generations of chickens and demonstrate a fully intact structure capable of its intended therapeutic function.
Project Leader, Roslin's Dr. Helen Sang, explained, "We have previously demonstrated that a reporter gene can be synthesized in the oviduct of laying hens, the source of egg white proteins. The significance of this new milestone is that we are now using a humanized anti-cancer antibody, which has been incorporated into the bird's DNA."
In other avian transgenic-related news, it was announced that a scientific article has been published in Drug Discovery Today (Volume 10, Number 3, February 2005). The article, titled "Transgenic chickens as bioreactors for protein-based drugs", reports on significant advances to develop avian transgenics.
Organizations
Other news from the department science
These products might interest you
Biostat STR by Sartorius
Biostat STR Generation 3 Bioreactors
Engineered for Ultimate Upstream Performance
Ambr® 250 HT Consumables by Sartorius
Efficient bioprocesses with single-use bioreactors
Minimise cleaning effort and maximise flexibility for cell and microbial cultures
Ambr® 250 Modular by Sartorius
Mini bioreactors for cell and gene therapies with high scalability
Maximise your process development with reliable single-use vessels
Brooks Instrument SLA Biotech-Serie by Brooks Instrument
Control bioprocesses efficiently and precisely with flow controllers for biotechnology applications
The SLA Biotech series has been developed specifically for the requirements in bioprocesses
Flexcell Systems by Dunn
Flexcell Cell Stretching Bioreactors for Life Science Research
Used in over 1300 laboratories worldwide, and cited in over 4000 research publications
SLAMf Biotech-Serie Massendurchflussregler by Brooks Instrument
SLAMf Mass Flow Controllers Designed Specifically for Biotech (IP66 / NEMA 4X)
Special equipment for biotech process plants, suitable for splash water and high-pressure cleaning
Get the life science industry in your inbox
From now on, don't miss a thing: Our newsletter for biotechnology, pharma and life sciences brings you up to date every Tuesday and Thursday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.