Immatics Receives Financing to Develop T-Cell Receptor Based Immunotherapies
- Progress its pipeline of adoptive cell therapies in a series of clinical trials. This will include the candidates IMA101, an ACTolog® endogenous T-cell therapy, and IMA201, an ACTengine® approach, based on transducing a patient’s own T-cells to express a tumor-specific exogenous T-cell receptor (TCR) and redirecting activated T-cells to the tumor sites.
- Continue to develop its pipeline of bispecific TCR candidates, with the aim to redirect and activate the T-cell response towards cancer cells expressing specific tumor targets.
- Continue the discovery and validation of novel tumor targets for cancer immunotherapy, using its world-leading XPRESIDENT® technology.
Peter Chambré, Chairman of Immatics, said: “We are very pleased to have been supported in this financing by our existing shareholders and a number of major new shareholders, including Amgen, with whom the Company signed a strategic collaboration earlier this year. During the period covered by this financing we expect to receive initial patient data from the current Immatics’ IMA101 and IMA201 adoptive cell therapy clinical trials, as well as commencing trials of further ACTengine® candidates.
We also expect to demonstrate proof of principle for our novel bispecific TCR candidates that, we believe, have significant potential in this emerging field. Immatics’ adoptive cell therapies and bispecific TCR candidates are tailored to address cancer targets identified and validated using XPRESIDENT®.”
Most read news
Organizations
Other news from the department science
Get the life science industry in your inbox
By submitting this form you agree that LUMITOS AG will send you the newsletter(s) selected above by email. Your data will not be passed on to third parties. Your data will be stored and processed in accordance with our data protection regulations. LUMITOS may contact you by email for the purpose of advertising or market and opinion surveys. You can revoke your consent at any time without giving reasons to LUMITOS AG, Ernst-Augustin-Str. 2, 12489 Berlin, Germany or by e-mail at revoke@lumitos.com with effect for the future. In addition, each email contains a link to unsubscribe from the corresponding newsletter.