Study sheds light on treating cancer
Using light to target and kill cancer cells alternatively without surgery
This study was jointly conducted by Prof. Tae-Hyuk Kwon (School Natural Science), Prof. Mi Hee Lim (School of Natural Science), and Prof. Hyun-Woo Rhee (School of Natural Science), and eight other researchers at UNIST.
In the study, the team developed photodynamic therapy (PDT) agent composed of Ir(III) complexes for cancer cells via a molecular design strategy for efficient ROS generation that accounted for appropriate energy levels and high emission quantum yields.
The team expects that their Ir(III) complexes could be used for additive-free photo-cross-linking in other fields beyound PDT.
Original publication
Jung Seung Nam, Myeong-Gyun Kang, Juhye Kang, Sun-Young Park, Shin Jung C. Lee, Hyun-Tak Kim, Jeong Kon Seo, Oh-Hoon Kwon, Mi Hee Lim, Hyun-Woo Rhee, and Tae-Hyuk Kwon; "Endoplasmic Reticulum-Localized Iridium(III) Complexes as Efficient Photodynamic Therapy Agents via Protein Modifications"; JACS; 2016
Original publication
Jung Seung Nam, Myeong-Gyun Kang, Juhye Kang, Sun-Young Park, Shin Jung C. Lee, Hyun-Tak Kim, Jeong Kon Seo, Oh-Hoon Kwon, Mi Hee Lim, Hyun-Woo Rhee, and Tae-Hyuk Kwon; "Endoplasmic Reticulum-Localized Iridium(III) Complexes as Efficient Photodynamic Therapy Agents via Protein Modifications"; JACS; 2016
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