PDS Biotechnology reports positive Phase I clinical trial results in proprietary HPV-Cancer Immunotherapy
Currently, pre-cervical cancer is treated by surgical removal of lesions however; PDS0101 could offer an effective non-surgical alternative. Results show that it primes and activates the body’s defense mechanisms (T-cells) to recognize, target, and kill precancerous and cancerous cells that display HPV viral proteins, which are responsible for over 99% of cervical cancers. The patient population tested were those most likely to develop invasive cancer as they had little to no pre-treatment immune responses to HPV-16.
The results are the first demonstration of PDS Biotechnology’s proprietary synthetic immunotherapy technology, Versamune’s®, application in human cancer. They also mirror preclinical data which showed strong T-cell responses and aggressive tumor regression with low doses of the product. The results mark an important step towards the development of next generation therapies to treat early and late stage cancers and suggest that Versamune® could be used by other immuno-oncology platform technologies.
Most read news
Organizations
Other news from the department research and development
Get the life science industry in your inbox
From now on, don't miss a thing: Our newsletter for biotechnology, pharma and life sciences brings you up to date every Tuesday and Thursday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.