New molecular probes that shed light on biological systems
Research describes the development of two new fluorescent probes for highly sensitive and selective identification of sulfane sulfurs. The probes were rationally designed to react selectively with sulfane sulfur compounds in a fast addition-cyclisation to form benzodithiolone and release a fluorophore. The scientists showed that they were able to detect fluorescence from the probes in cultured cells, paving the way for development of non-destructive probes for sulfane sulfurs that can be used in living cells and even in vivo.
Original publication
W Chen et al, Chem. Sci., 2013
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Original publication
W Chen et al, Chem. Sci., 2013
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