Genetically active nano-calcium phosphate paste for bioactive bone grafts

19-Feb-2013 - Germany

A genetically active nanoparticle calcium phosphate bone paste has been developed by scientists working in Germany, who claim that the material can act as a gene-delivery agent as well as a biodegradable bone graft.

Calcium phosphates make up the majority of synthetic bone substitution materials, owing to their similarity to bone itself. This newly developed material is made from calcium phosphate nanoparticles that also carry short chains of DNA into bone cells through transfection. This DNA encodes for proteins and growth factors that enhance the bioactivity of bone grafts, and help the material integrate into the body.

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