Horizon and Boehringer Ingelheim enter oncology research service collaboration
Under the terms of the collaboration, Horizon will evaluate compounds across a broad panel of X-MAN isogenic models and 2D/3D phenotypic assays, and will provide an FTE.
Horizon will also apply its proprietary genome editing technology GENESIS™ to develop human isogenic disease model cell lines, according to Boehringer Ingelheim’s specifications. Using GENESIS, Horizon is able to alter any endogenous gene sequence of human or mammalian cell lines quickly, reliably and without unwanted and confounding genotypes and/or phenotypes. The resulting high quality cell lines accurately model the disease-causing mutations found in patients.
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