The United States, New Zealand & Mexico Issue Patent for New Allon Platform
This new platform is derived from a protein involved in the function of microtubules that are critical to the correct structure and communication of neurons in the brain. Individual peptides derived from this platform have shown memory improvement in mice with compromised cognition caused by the aggregation of the tau protein. One of the main functions of the tau protein is to stabilize microtubules and Allon’s preclinical studies have shown that peptides from this new family have the potential to inhibit tau aggregation.
These patents cover a family of peptides comprising an entirely new class of compounds distinct from Allon’s two existing neuroprotective technology platforms, activity-dependent neuroprotective protein (ADNP) and activity-dependent neurotrophic factor (ADNF). The company’s lead product candidate, davunetide, is based on ADNP.
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