Horizon Discovery and Domainex Ltd Collaborate to Support Lead Optimization Oncology Program
Horizon’s isogenic cell lines accurately modeling tumor mutations to be used to profile lead compounds
08-Aug-2012
- United Kingdom
Profiling of Domainex’s lead TBK1/IKKe dual inhibitor molecules against the X-MAN cell lines will enable identification of the effect of individual mutations on drug activity and resistance and prediction of which patient sub-groups will respond. This will help guide the medicinal chemistry optimization program and will provide important patient stratification data for future partnering.
Financial terms of the agreement are not disclosed.
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