Ironwood Pharmaceuticals and Bionomics announce collaboration research

Companies to Collaborate on Central Nervous System Disorder Opportunity

06-Jan-2012 - Australia

Ironwood Pharmaceuticals, Inc. and Bionomics Limited announced that they entered into a collaboration, research, and licensing agreement that will enable Ironwood to develop and commercialize Bionomics’ investigational anti‐anxiety compound BNC210 and other related compounds. The goal of the collaboration is to evaluate the compound’s potential as a novel anti‐ anxiety treatment. Data from several preclinical studies indicate that BNC210 has anti‐anxiety activity without the sedative side effects that are typical of benzodiazepines, a class of drugs used to treat anxiety. These data are further strengthened by Phase 1 clinical studies, where pharmacodynamic markers of anti‐anxiety activity without sedation were observed in healthy volunteers who took a single dose of BNC210. This collaboration furthers both companies’ commitment to develop innovative treatments for patients with high unmet need.

Under the terms of the agreement, the companies will collaborate on initial research and Ironwood will be responsible for worldwide development and commercialization of all products incorporating BNC210 or other licensed compounds, including funding of clinical trials. Pending achievement of certain development and regulatory milestones, Bionomics could receive up to US$345 million in upfront and milestone payments and research funding, as well as royalties on sales of products incorporating BNC210 and other related compounds. Over the next 24 months, Bionomics may receive up to US$13 million in research funding and milestone payments, including an initial payment of US$3 million.

https://www.bionity.com/en/news/135836/ironwood-pharmaceuticals-and-bionomics-announce-collaboration-research.html