AFFiRiS AG strengthens its development pipeline with the foundation of a Christian-Doppler-Laboratory
AFFiRiS AG is the industrial Partner of the newly-established Christian-Doppler-Laboratory for Cardiometabolic Immunotherapy. In partnership with the Medical University of Vienna the laboratory will work on basic research for the development of a vaccination therapy against type 2 diabetes and cardiovascular diseases. The reason for AFFiRiS' commitment is its decision to establish an additional top priority field.
AFFiRiS AG announced its role as industrial partner in the newly-established Christian-Doppler-Laboratory for Cardiometabolic Immunotherapy at the Medical University of Vienna. Headed by Prof. Thomas Stulnig, Department of Internal Medicine III at the General Hospital Vienna, the Christian-Doppler-Laboratory (CD-Laboratory) will work on chronic inflammatory processes of adipose tissue and of the cardio-vascular system and thereby contribute to the basic research for a vaccination therapy against Type 2 Diabetes mellitus and cardio-vascular diseases. The initial plan for the CD-Laboratory is for seven years and is financed by public funding and AFFiRiS as an investor.
Additionally, AFFiRiS provides the CD-Laboratory with its proprietary AFFITOME®-technology, which allows the development of highly specific therapeutic vaccines and is the basis for all previous achievements of AFFiRiS in the development of vaccinations. These have to date focused mainly on neurodegenerative diseases. The collaboration with the CD-Laboratory now implements a new field of attention: Vaccines against inflammatory diseases. CEO and co-founder of AFFiRiS, Walter Schmidt comments: "Inflammatory processes are more and more identified as a contributory cause of many chronic diseases. Taking this into account, we are now investing in the basic research of the corresponding pathophysiological principles, so that our technology can contribute to combating inflammatory-induced chronic diseases. This perfectly fits with our strategy of sustainable diversification and risk spreading."
The CD-Laboratory will initially focus its activities on the evaluation of relevant target structures with functions in the immune system and inflammatory processes. These same structures will be investigated and characterized within the framework of the CD-Laboratory. Günther Staffler, Head of the Immunology Department at AFFiRiS, adds: "There is increasing evidence that some of the body's own structures are involved into the cause of inflammatory reactions of the adipose tissue. As a consequence, these reactions contribute to the emergence of Type 2 Diabetes and cardio-vascular diseases in a way that's still not fully understood. The underlying fundamental inflammatory mechanisms will now be investigated at the CD-Laboratory. It will also be explored, whether and how an active immunization approach based on our AFFITOME®-platform-technology can unfold its therapeutic efficacy/impact."
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