caprotec bioanalytics Announces Issuance In Europe of All Core Patents of Its CCMS Technology

04-Mar-2011 - Germany

caprotec bioanalytics GmbH announced that the European Patent Office has granted the last of three core patents protecting its proprietary Capture Compound mass spectrometry (CCMS) technology.

CCMS offers a novel and direct way to investigate small molecule - protein interactions resulting in a significant functional reduction of proteome complexity. The core of the CCMS technology consists of tri-functional small molecules called Capture Compounds™.  These Capture Compounds enable the direct isolation and identification of selected proteins, including membrane proteins, out of any complex biological sample.

An important application of the CCMS technology is to profile small molecule drug - protein interactions in the human proteome to discover or confirm relevant protein drug targets, the mode of drug action, and off-target proteins potentially causing adverse side effects in humans.

The newly granted European Patent No. EP 1583972 titled “Methods for Identifying Drug Non-targets” covers the use of CCMS technology for lead optimization and risk assessment of candidate drugs to make a go or no-go decision to enter the clinical trial phase.  The European Patent No.  EP  1485707 titled “Compounds and Methods for Analyzing the Proteome” covers Capture Compounds and methods to discover protein biomarkers for diagnostic applications. European Patent No. EP 1502102 titled “Compounds and Methods for Analyzing the Proteome” covers an array-based application of CCMS technology.  Equivalent patents have been issued in many major countries.

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