Understanding how cells migrate
A broad spectrum of technology and biology is included: topics covered include neutrophil and Dictyostelium chemotaxis, mechanobiology, amoeboid migration and the application of microfluidics to the study of directed cell migration. Technology for in vivo studies and improved methods for studying axon guidance are also included. Finally, the role of chemotaxis in cancer is examined.
“The integration of technology and biology has matured further here than in many other areas of biological study” says David Beebe from the University of Wisconsin-Madison’s department of biomedical engineering. “The papers in this issue highlight advances in technology that allow investigators to address fundamental questions about directed migration that provide insight into basic mechanisms and provide tools for drug discovery and clinical intervention” he added.
Original publication: David J. Beebe and Anna Huttenlocher, Integr. Biol., 2010, 2, 559-560.
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