Raptor Pharmaceutical Licenses Intellectual Property Related to Huntington's Disease

04-Jun-2010 - USA

Raptor Pharmaceutical Corp. announced that the Company has acquired an exclusive worldwide license to intellectual property related to the potential treatment of Huntington's disease from the Weizmann Institute of Science in Israel and Niigata University in Japan. In addition, Raptor has added Professor Lawrence Steinman, M.D., an inventor on the Weizmann patent, to its Advisory Board.

The Weizmann and Niigata patents cover the use of transglutaminase inhibitors, a class of molecules chemically similar to cysteamine, in the potential treatment of Huntington's Disease and other neurological disorders. These patents add to Raptor's portfolio of intellectual property related to its programs utilizing DR Cysteamine, Raptor's proprietary formulation of delayed-release cysteamine bitartrate, licensed exclusively, with worldwide rights, from the University of California, San Diego.

Ted Daley, President of Raptor's Clinical Division, stated, "This exclusive license covering the Weizmann and Niigata patents significantly strengthens and expands our proprietary position as the compounds claimed in these patents are closely related to our lead clinical compound DR Cysteamine. Additionally, this strategic move to enhance our intellectual property position coincides with our planned clinical trial of DR Cysteamine in collaboration with The Centre Hospitalier Universitaire d'Angers ("CHU d'Angers") for the potential treatment of Huntington's Disease, as well as our future plans to explore potential treatments for multiple indications utilizing cysteamine and DR Cysteamine."

Raptor plans to initiate a Phase II clinical trial this summer of DR Cysteamine in patients with Huntington's Disease under a collaboration agreement with CHU d'Angers of France. The Company is also developing DR Cysteamine as a potential treatment for nephropathic cystinosis ("cystinosis") and non-alcoholic steatohepatitis ("NASH").

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