Lifespin partners with the Leipzig Research Center for Civilization Diseases to obtain deep clinical insights for obesity and diabetes

27-Apr-2023 - Germany

Lifespin GmbH announced that it has entered into a significant scientific collaborative agreement with Leipzig Research Center for Civilization Diseases (LIFE) and Leipzig Medical Biobank to study whether certain patients who are obese or have diabetes have identifiable variations in their metabolism that may indicate predisposed risk for these conditions.

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Lifespin, an emerging medical technology company, has built one of the largest and most comprehensive databases of metabolic health profiles across healthy and diseased individuals covering multiple age and biological sex groups as well as specific diseases in neurology, oncology, and inflammation.  Utilizing proprietary software and A.I., Lifespin is working to launch new products and services (SaaS) that enable clinicians, researchers, drug development organizations, and other entities to identify various disease states and health and wellness markers based on a patient’s metabolism.

The Leipzig Research Center for Civilization Diseases and Leipzig Medical Biobank have agreed to provide Lifespin with access to 8,000 patient samples from the LIFE Adult study, a long-term, population-based cohort study.  The LIFE study includes people from the Leipzig adult population ranging in age from 40 to 80 years, who are being comprehensively studied for disease risks, frequency of more common diseases, such as obesity and diabetes, and the influence of certain lifestyle and environmental factors on their health. A primary goal of the study is to identify previously unknown risk factors for developing non-communicable diseases (NCDs), from which new early detection methods could then be developed.

“This partnership will help to shed new light on one of the largest issues in today’s societies, namely the increase of non-communicable diseases such as obesity and diabetes which can lead to downstream diseases such as inflammation, cancer, or cardiovascular diseases, and the potential ability to identify risk factors that may appear as variations in a person’s metabolism,” said Lifespin’s CEO, Dr. Ali Tinazli.

“Given the broader aging of our population, and the growing onset of these types of NCDs as we get older, identifying new ways such as our metabolism to predict and manage diseases of this nature are urgently needed.”

The metabolic profiles created by Lifespin will be returned to the Leipzig Research Center for Civilization Diseases and further expand the research database already established by LIFE. These data will be available to researchers at Leipzig University Medical Center, but also to external cooperation partners for follow-up analyses and further scientific projects.

“This important collaboration brings together the complementary, strong assets of both partners,” said Dr. Roland Geyer, COO of Lifespin GmbH. “Utilizing access to the phenotypic data collected in the LIFE study, our Lifespin technology will be able to generate metabolite profiles of this cohort that can then be compared to Lifespin’s comprehensive healthy baseline, potentially enabling the identification of biomarkers or metabolite signatures that may be helpful in predicting risk factors for some NCDs such as type 2 diabetes.”

“Our scientific cooperation with Lifespin supports our central goal to provide deep insights into the relationships between genetic predisposition, personal lifestyle, and environmental factors with individual health status and the development of lifestyle diseases such as type 2 diabetes mellitus at the population level,” said Dr. Ronny Baber, Head of Leipzig Medical Biobank.

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