TRIN Pharma starts phase I clinical trial of TRIN 2755 in solid tumors

11-Nov-2009 - Germany

TRIN Pharma GmbH announced that BfArM, the German regulatory authority, has approved the start of a Phase I clinical trial of TRIN 2755 in solid tumors. The trial will be conducted at two clinical sites in Germany, Westdeutsches Tumorzentrum in Essen and Tumor Biology Center in Freiburg.

TRIN 2755 is based on a new chemistry with solid IP platform. Preclinical experiments have demonstrated excellent activity of TRIN 2755 in xenograft models of human malignant melanoma, breast and colon cancer, including drug resistant tumors. The vast majority of animals treated with TRIN 2755 reached complete and stable remission at well tolerated doses. TRIN 2755 exerts rapid metabolic clearance while at the same time tolerability was very good in early toxicology studies.

Stefan Wohlfeil, CEO of TRIN Pharma said: "We are very excited about the start of the clinical development of our lead molecule. We believe that TRIN 2755 has a high likelihood of showing clinical benefit and to become an important part of anti-cancer therapy."

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