Santhera Enters Agreement with Columbia University to Investigate Additional Potential of Catena in MELAS
The MELTIMI (MELAS Trial of Idebenone using MRS) trial is a Phase II double-blind, placebo-controlled study investigating the safety and efficacy of two doses of Catena® (INN: idebenone) versus placebo. The primary endpoint of the proof-of-concept study is the change in cerebral lactate concentration from baseline to week four as assessed by Magnetic Resonance Spectroscopy (MRS). The MELTIMI study will also investigate additional endpoints such as venous lactate levels, fatigue and quality of life. The lactate level is considered a viable biomarker associated with the neurological impairment in MELAS. Overall, the MELTIMI study will enroll 21 patients aged between 8 and 65 years.
The MELTIMI study is being performed at Columbia University. Under the agreement, the Neurological Institute of Columbia University is conducting the clinical trial while Santhera is supplying the study medication and contributes data management and other support. The Company has exclusive rights to the data for regulatory purposes.
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Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!
Topic World Spectroscopy
Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!