Membrane proteins - 83 News

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Membrane proteins - 83 News

Tip: You can further refine your news selection by departments, organizations, countries and industries.

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A protein on cancer cells supports immune response against tumors

Surprising discovery

19-Sep-2023 - Scientists from the German Cancer Research Center (DKFZ) identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important "co-stimulatory" factor that enhances the activation of T cells, thus improving the immune response against ...

membrane proteins cancer cancer cells
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The armorers: How dendritic cells activate the immune system

Thanks to this “armoring function”, dendritic cells constitute a ray of hope for personalized immunotherapy

18-Jul-2023 - As part of the immune system, dendritic cells are essential for fighting body cells that have degenerated or are infected with a virus. They trigger an immune response by presenting protein fragments, for example of viruses, to T cells. In so doing, they activate the latter so that these ...

membrane proteins dendritic cells immune system
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A Quality-Conscious Protein

Discovery could lead to new therapeutic approaches for Alzheimer’s and other protein-misfolding diseases

06-Dec-2022 - Researchers have identified a new function of a well-known enzyme: the signal peptidase complex is responsible for the quality control of membrane proteins. The discovery of this new function for a key enzyme in cell biology has been published in ‘Science’ and could lead to new therapeutic ...

membrane proteins cell biology endoplasmic reticulum
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New Detergents for Drug Research

So far, it is unclear why it is only possible to make intact membrane proteins available for drug research with the help of certain detergents

02-Sep-2022 - Researchers at TU Dortmund University and Freie Universität Berlin have developed a process for producing new detergents for drug research. The purpose of the new detergents is to separate sensitive proteins from biomembranes so that they can be studied in detail for their use in drug research. ...

membrane proteins active ingredient research biomembranes
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Palmitoylation, a new target for anti-cancer drugs

By developing a tool to visualize the membrane association and activation status of normal and oncogenic proteins, scientists at the UNIGE have established the basis for innovative drug discovery

29-Apr-2022 - Peripheral membrane proteins have the particularity of temporarily binding to cell membranes, a necessary step for them to be able to fulfil their biological function. To do this, certain enzymes that catalyse their lipid modification come into action. This process is called“palmitoylation”. ...

membrane proteins cancer cancer drugs
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Strategy designed to identify therapeutic targets in triple-negative breast cancer

Localizes proteins in the membrane of tumor cells and then targets them in a specific way.

26-Apr-2022 - Research led by the Cancer Research Center (CIC), a joint center of the Spanish National Research Council (CSIC) and the University of Salamanca (USAL), has described a strategy for identifying proteins in the membrane of tumor cells and then attacking these cells using specific antibodies ...

membrane proteins proteins triple-negative breast cancer
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Light-powered microbes are super-producing chemical factories

New method allows bacteria to use light for external energy to accelerate biomanufacturing of target compounds without disrupting the host microorganism's natural metabolism

14-Apr-2022 - Sharing is key to living in society, whether it’s toddlers sharing toys or nations sharing natural resources; but there’s no avoiding the fact that one side getting more means that the other side gets less. Now, researchers from Osaka University, in collaboration with the University of Shizuoka ...

membrane proteins biomanufacturing biosynthesis
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Methane-eating bacteria convert greenhouse gas to fuel

State-of-the-art method reveals never-before-seen atomic structures controlling the process

21-Mar-2022 - Methanotrophic bacteria consume 30 million metric tons of methane per year and have captivated researchers for their natural ability to convert the potent greenhouse gas into usable fuel. Yet we know very little about how the complex reaction occurs, limiting our ability to use the double benefit ...

membrane proteins bacteria biocatalysts
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Pop-up factories beneath the cell membrane

Scientists have long regarded the cytosol liquid inside a cell as a large “swimming pool” in which everything floats around freely: But it seems that previously unknown structures

17-Mar-2022 - In a study published in Cell, MDC researchers show how a cell is able to process hundreds of signals simultaneously. Andreas Bock and his colleagues believe their findings will open up a whole new field of research in cell biology. A living cell is exposed to a variety of stimuli. Countless ...

membrane proteins cell biology cell membranes
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Prestigious award for the pioneers of optogenetics

Dieter Oesterhelt, Emeritus Director at the Max Planck Institute of Biochemistry, is being honoured with the Lasker Basic Medical Research Award 2021 together with Peter Hegemann and Karl Deisseroth

27-Sep-2021 - Dieter Oesterhelt from the Max Planck Institute of Biochemistry, Peter Hegemann from Humboldt University and the U.S. American Karl Deisseroth from Stanford University will receive the Albert Lasker Basic Medical Research Award 2021 for the discovery of light-sensitive proteins in the membrane of ...

membrane proteins bacteriorhodopsin awards
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