Bruker to acquire the NanoString business in an asset deal

24-Apr-2024 - Bruker Corporation announced that it has entered into a definitive acquisition agreement with NanoString Technologies, Inc., headquartered in Seattle, Washington, a leading provider of solutions for spatial transcriptomics and gene expression analysis. Under the asset purchase agreement, Bruker ...

Does COVID-19 accelerate the aging process of the brain?

Severe COVID-19 linked with molecular signatures of brain aging

13-Dec-2022 - Although COVID-19 is primarily a respiratory disease, neurological symptoms have been described in many COVID-19 patients, including in recovered individuals. Patients report symptoms including brain fog or lack of focused thinking, memory loss and depression, and scientists have demonstrated ...

Blood-based test accurately identifies viral infection before symptoms develop

The study, conducted prior to COVID-19, has broad potential for pandemic responses

29-Sep-2020 - A team of Duke Health scientists have identified biomarkers that accurately identify numerous viral infections across the clinical stages of disease, advancing a potential new way to guide treatment, quarantine decisions, and other clinical and public health interventions in the setting of ...

Evolution in real-time: How bacteria adapt to their hosts

Some bacteria become increasingly infectious when they have to move from cell to cell in order to survive

20-Aug-2020 - Bacteria that invade animal cells in order to multiply are widespread in nature. Some of these are pathogens of humans and animals. In the environment, they are often found inside unicellular organisms. A research team led by Matthias Horn at the Centre for Microbiology and Environmental Systems ...

Machine-learning driven findings uncover new cellular players in tumor microenvironment

Involvement of adipocytes in nivolumab response in ipilimumab resistant melanoma patients

18-Oct-2018 - New findings presented by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy. Once validated, the findings could ...

New software processes huge amounts of single-cell data

Comprehensive analysis of large gene-expression datasets

13-Feb-2018 - Scientists from the Helmholtz Zentrum München have developed a program that is able to help manage enormous datasets. The software, named Scanpy, is a candidate for analyzing the Human Cell Atlas. “It’s about analyzing gene-expression data of a large number of individual cells,” explains lead ...

Shedding light on protein interaction networks in a developing organism

28-Jul-2017 - Researchers succeeded for the first time in mapping protein-protein interactions in living developing plant roots. The findings were made by three international research groups led by the department of Plant Developmental Biology at Wageningen University and Research. The work is considered a ...

Breast cancer: finding the smoking gun

A new method developed at Vanderbilt may help “inventory” all tumor-promoting genes.

22-Jul-2016 - Many genes are associated with cancer. The trick is proving they actually promote tumor formation. One approach, detailed by Ian Macara , Ph.D., and colleagues is an in vivo “gain-of-function” screen. The researchers used a gene “library” (complementary DNA carried by lentivirus) to increase the ...

Brain development: Fate of brain progenitor cells hinges on getting the timing right

02-May-2014 - Just like musicians in a philharmonic orchestra look to the conductor for their cues, stem cells in charge of generating the dazzling number and variety of cells that build the developing brain rely on molecular signals to get the timing right. Now, scientists at the Leibniz Institute for Age ...

Researchers successfully develop animal free methods for testing chemical compounds for allergens

EU-funded research project developing in vitro test strategies to reduce or replace animal testing use gene expression analysis software

09-Apr-2013 - As of march 2013 there is a ban in the European Union (EU) on animal testing of ingredients for cosmetics. The ban applies to all new cosmetics and their ingredients sold in the EU, regardless of where in the world testing on animals was carried out. The 27 EU countries have had a ban on such ...