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Usual interstitial pneumonia



Usual interstitial pneumonia, commonly abbreviated UIP, is the name of a histopathological pattern seen in diffuse lung diseases. Diffuse lung diseases are also referred to as interstitial lung diseases.

UIP is a type of idiopathic interstitial pneumonia. Sometimes, confusingly, it is used as a synoym for idiopathic pulmonary fibrosis.

Contents

Differential diagnosis

UIP is seen in:[1]

Histologic appearance

UIP is characterized by:

  • interstitial inflammation,
  • fibroblast foci,
  • (microscopic) honeycombing and
  • patchy lesional distribution (heterogeneous areas of abnormal and normal lung).

History and application of term

UIP, as a term, first appeared in the pathology literature. It was coined by Averill Abraham Liebow.[3]

It is sometimes, confusingly, used to refer to idiopathic pulmonary fibrosis, one of its many clinical correlates.

Pneumonia misnomer?

The definition of "pneumonia" is often described as a '... lung inflammation caused by a virus, bacteria or irritant.'[4]

Etymologically, the usage of "pneumonia" in UIP is correct; the word "pneumonia" is derived from "pneumon" (lung) and the suffix "-ia" (condition).[5]

See also

References

  1. ^ Leslie KO, Wick MR. Practical Pulmonary Pathology: A Diagnostic Approach. Elsevier Inc. 2005. ISBN 978-0-443-06631-3.
  2. ^ Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC (2000). "Pulmonary drug toxicity: radiologic and pathologic manifestations". Radiographics : a review publication of the Radiological Society of North America, Inc 20 (5): 1245–59. PMID 10992015.
  3. ^ Averill Abraham Liebow. whonamedit.com. URL: http://www.whonamedit.com/doctor.cfm/2548.html. Accessed on: November 12, 2007.
  4. ^ Pneumonia. dictionary.com. URL: http://dictionary.reference.com/browse/pneumonia. Accessed on: November 14, 2007.
  5. ^ Pneumonia. Stedman's Medical Dictionary. URL: http://www.emedicine.com/asp/dictionary.asp?keyword=pneumonia. Accessed on: November 12, 2007.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Usual_interstitial_pneumonia". A list of authors is available in Wikipedia.
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