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Tralomethrin



Tralomethrin
Chemical name CYANO(3-PHENOXYPHENYL)METHYL 2,2-DIMETHYL-3-(1,2,2,2-
TETRABROMOETHYL)CYCLOPROPANECARBOXYLATE
CYCLOPROPANECARBOXYLICACID, 2,2-DIMETHYL-3-(1,2,2,2-
TETRABROMOETHYL)-, CYANO(3-PHENOXYPHENYL)METHYL
ESTER
Chemical formula C22H19Br4N1O3
Molecular weight 665.0000
Melting point -
Boiling point 138 °C - 148 °C
CAS number 66841-25-6
SMILES C(Br)(C(Br)(Br)Br)C1C(C)(C)C1C(=O)OC(C#N)c1cccc(c1)Oc1ccccc1

Properties

Tralomethrin is a colourless organic chemical.

Tralomethrin has potent insecticidal properties; it kills by modifying the gating kinetics of the sodium channels in neurons, increasing the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasming, paralysis, and eventual death. Insects with certain mutations in their sodium channel gene may be resistant to Tralomethrin and other similar insecticides.

Tralomethrin is also effective against most members of class Arachnida as well as insects, in addition studies by the EPA on the ecotoxicity of Tralomethrin shows results as follows:

Tralomethrin Ecotoxicity
Organism Group Effects Noted
Aquatic plants Accumulation
Crustaceans Intoxication, Population
Fish Accumulation, Mortality, Population
Insects Mortality, Population
Molluscs Intoxication
Zooplankton Intoxication, Mortality, Population

Impact on human health

Tralomethrin is a pyrethroid compound. The symptoms of poisoning with pyrethroid compounds are all alike,

  • Irritation of skin and eyes.
  • Irritability to sound or touch, abnormal facial sensation, sensation of prickling, tingling or creeping on skin, numbness.
  • Headache, dizziness, nausea, vomiting, diarrhea, excessive salivation, fatigue.
  • In severe cases: fluid in the lungs and muscle twitching may develop. Seizures may occur and are more common with more toxic cyano-pyrethroids.

References

    • http://iaspub.epa.gov/srs/srs_proc_qry.navigate?P_SUB_ID=357483
    • http://www.arsusda.gov/acsl/services/ppdb/textfiles/TRALOMETHRIN
    • http://www.pesticideinfo.org/List_AquireAll.jsp?Rec_Id=PC34911
     
    This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tralomethrin". A list of authors is available in Wikipedia.
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