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Tocopheryl acetate

Tocopheryl acetate

IUPAC name	[(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate
Other names	Tocopherol acetate Vitamin E acetate
Identifiers
CAS number	58-95-7
PubChem	86472
SMILES	CC1=C2C(O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CC2)=C(C)C(C)=C1OC(C)=O
Properties
Molecular formula	C₃₁H₅₂O₃
Molar mass	472.743 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Tocopheryl acetate, also known as vitamin E acetate, is a common vitamin supplement with the molecular formula C₃₁H₅₂O₃ (for 'α' form). It is the ester of acetic acid and tocopherol (vitamin E). It is often used in dermatological products such as skin creams.

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Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product. It is believed that the acetate is slowly hydrolyzed once it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.^[1]

References

^ Beijersbergen van Henegouwen G, Junginger H, de Vries H (1995). "Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat)". J Photochem Photobiol B 29 (1): 45-51. PMID 7472802.

Category: Vitamins