My watch list

Tocopheryl acetate

Tocopheryl acetate

IUPAC name	[(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate
Other names	Tocopherol acetate Vitamin E acetate
Identifiers
CAS number	58-95-7
PubChem	86472
SMILES	CC1=C2C(O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CC2)=C(C)C(C)=C1OC(C)=O
Properties
Molecular formula	C₃₁H₅₂O₃
Molar mass	472.743 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Tocopheryl acetate, also known as vitamin E acetate, is a common vitamin supplement with the molecular formula C₃₁H₅₂O₃ (for 'α' form). It is the ester of acetic acid and tocopherol (vitamin E). It is often used in dermatological products such as skin creams.

Additional recommended knowledge

How to ensure accurate weighing results every day?

How to quickly check pipettes?

Don't let static charges disrupt your weighing accuracy

Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product. It is believed that the acetate is slowly hydrolyzed once it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.^[1]

References

^ Beijersbergen van Henegouwen G, Junginger H, de Vries H (1995). "Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat)". J Photochem Photobiol B 29 (1): 45-51. PMID 7472802.

Category: Vitamins