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Thyronamine

Thyronamine


Identifiers
CAS number	500-78-7
PubChem	3083601
MeSH	thyronamine
Properties
Molecular formula	C₁₄H₁₅NO₂
Molar mass	229.274 g mol⁻¹
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).

The group includes:

Thyronamine (T0AM)
3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), a G protein-coupled receptor located in the cell membrane.
3,5-Diiodothyronamine (T2AM)
3,5,3'-Triiodothyronamine (T3AM)

See also