Temefos

Temefos or Temephos (trade name Abate) is an organophosphate larvicide used to treat water infested with disease-carrying fleas. It is also used to control mosquito, midge, and black fly larvae.

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As with other organophosphates, temephos affects the central nervous system through inhibition of cholinesterase. In larvae, this results in death before reaching the adult stage.

In the developing world where the vector-borne disease dengue fever is endemic, temephos is widely used and applied by both private and public pest control in areas of standing water where the Aedes aegypti mosquito breeds in order to reduce the population of this disease-carrying insect.

Resistance to temephos by A. aegypti has been seen in Brazil. The Brazilian Aedes aegypti resistance monitoring program detected temephos resistance in A. aegypti populations from several localities in the country in 1999 (Funasa 2000, Lima et al. 2003). In 1999, mosquitoes from the city of Rio de Janeiro were already resistant to temephos (Lima et al. 2003).

References

• New York Times article covering its application in Africa

• Lima JB, Da-Cunha MP, Da Silva RC, et al (2003). "Resistance of Aedes aegypti to organophosphates in several municipalities in the State of Rio de Janeiro and Espírito Santo, Brazil". Am. J. Trop. Med. Hyg. 68 (3): 329-33. PMID 12685640.

• Abate Product Information