My watch list

Tazobactam


Tazobactam
Systematic (IUPAC) name
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3- (triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid
Identifiers
CAS number	89786-04-9
ATC code	J01CG02
PubChem	?
DrugBank	EXPT03012
Chemical data
Formula	C₁₀H₁₂N₄O₅S
Mol. mass	300.289 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin® or Zosyn®. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

Additional recommended knowledge

Safe Weighing Range Ensures Accurate Results

Don't let static charges disrupt your weighing accuracy

What is the Correct Way to Check Repeatability in Balances?

Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.

v • d • e Antibacterials for systemic use: beta-lactam antibiotics - penicillins (J01C)
Antibiotics	Amoxicillin • Ampicillin • Azlocillin • Carbenicillin • Cloxacillin • Dicloxacillin • Flucloxacillin • Mezlocillin • Nafcillin • Piperacillin • Pivampicillin • Ticarcillin
Beta-lactamase inhibitors	Sulbactam • Tazobactam • Clavulanic acid
Combinations	Ampicillin/sulbactam (Sultamicillin) • Co-amoxiclav