Table of medication secernated in kidney

This is a table of medication secernated (secreted) in kidney.

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Acid medication are, because of pH parturition, secreted to a higher extent when urine is basic. In the same way, basic medications are secreted to a higher extent when urine is acidic.

Medication	Location	Acid or base ^[1]	anion or cation^[2]	Percentage excreted^[3]
para-aminohippurate	proximal tubule^[4]	Acid	anion
furosemide	proximal tubule^[4]	Acid	anion	100-75
glucuronic acid-conjugates	proximal tubule^[4]	Acid
glycine conjugates	proximal tubule^[4]	Acid
indometacin	proximal tubule^[4]	Acid	anion
methotrexate	proximal tubule^[4]	Acid		100-75
penicillin	proximal tubule^[4]	Acid	anion	75-50 (benzylpenicillin)
probenecid	proximal tubule^[4]	Acid	anion
sulphate conjugates	proximal tubule^[4]	Acid
thiazide diuretics	proximal tubule^[4]	Acid
uric acid	proximal tubule^[4]	Acid
amiloride	proximal tubule^[4]	Base	cation
dopamine	proximal tubule^[4]	Base
histamine	proximal tubule^[4]	Base
mepacrine	proximal tubule^[4]	Base
morphine	proximal tubule^[4]	Base	cation
pethidine	proximal tubule^[4]	Base
quaternary ammonium compounds	proximal tubule^[4]	Base
quinine	proximal tubule^[4]	Base	cation
5 hydroxytryptamine	proximal tubule^[4]	Base
triamterene	proximal tubule^[4]	Base
gentamicin				100-75
atenolol				100-75
digoxin				100-75
cimetidine			cation	75-50
tetracycline				75-50 (oxytetracycline)
neostigmine				75-50
propantheline				~50
tubocurarine				~50
acetazolamide	proximal tubule^[5]		anion
chlorothiazide	proximal tubule^[5]		anion
saccharin	proximal tubule^[5]		anion
salicylate	proximal tubule^[5]		anion
atropine	proximal tubule^[5]		cation
NMN	proximal tubule^[5]		cation
paraquat	proximal tubule^[5]		cation
procainamide	proximal tubule^[5]		cation
tetraethylammonium	proximal tubule^[5]		cation
chlorpromazine	proximal tubule^[5]		cation

References

^ Unless else specified in table boxes, then ref is Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 112
^ Unless else specified in table boxes, then ref is Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 802
^ Unless else specified in table boxes, then ref is Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 113
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 112
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 802

v • d • e Urinary system, physiology: renal physiology and acid base physiology
Filtration	Renal blood flow - Ultrafiltration - Countercurrent exchange
Hormones affecting filtration	Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Secretion/clearance	Pharmacokinetics - Clearance of medications
Reabsorption	Solvent drag -Na⁺ - Cl^- -urea -glucose -oligopeptides -protein
Endocrine	Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysis	Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance (Effective renal plasma flow - Extraction ratio)
Acid base physiology	Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas
Buffering/compensation	Bicarbonate buffering system - Respiratory compensation - Renal compensation