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Synaptic pharmacology



Synaptic pharmacology is the study of drugs that act on the synapses. It deals with the composition, uses, and effects of drugs that may enhance (receptor) or diminish (blocker) activity at the synapse, which is the junction across which a nerve impulse passes from an axon terminal to a neuron, muscle cell, or gland cell.

A partial list of pharmacological agents that act at synapses follows.

Synaptic pharmacology
Channel, Receptor, or Phenomenon Antagonist or Blocker
adenosine DCPGX, ZM241385, anoxinine
AMPA-R NBQX
AMPA-R desensitization cyclothiazide (CTZ)
cannabinoid AM-251
GABA-A bicuculline [1], gabazine [2]
GABA-B CGP-54626
glycine strychnine
kainate R ..
metabotropic GluR, broad MCPG [3], pertussis toxin, NEM
muscarinic AChR atropine, Scopolamine
nicotinic AChR bungarotoxin, curare, DhBe
NMDA-R APV
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Synaptic_pharmacology". A list of authors is available in Wikipedia.
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