My watch list
my.bionity.com  

my.bionity.com

With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.

  • My watch list
  • My saved searches
  • My saved topics
  • My newsletter
Register free of charge
Login  
eng  
DeutschEnglishFrançaisEspañol

Kim Sung-Hou



 This article or section's grammar usage needs improvement.
Please improve this article in accordance with Wikipedia's .
This is a Korean name; the family name is Kim.
Kim Sung-Hou
Hangul김성호
Hanja金聖浩

Kim Sung-Hou Ph.D. is a Korean-born American crystallographer and protein biophysicist. Dr. Kim reported first 3D structure of tRNA with A. Rich in 1973.[1] He also published many papers on the structures of protein molecules including Ras.[2] He is a member of U.S. National Academy of Science since 1994. He is currently a professor and a senior scientist at chemistry department of U.C. Berkeley and Lawrence Berkeley National Laboratory(LBL), respectively.

Controversy over structure of tRNA

Main article: tRNA history

Therer had been some intense competition among several groups worldwide for solving the 3D structure of tRNA during sixties and early seventies. Final round of that was between MIT's Rich group and Aaron Klug's group at Cambridge. Dr. Kim first published 4Å structure in Science in 1973.[1] Next year his group came up with 3Å structure.[3] But from Klug group's argument,[4] after a symposium held in June 1974, where Kim's group arguably heard the different results of Klug's experiment, they rewritten and published revised paper on 3Å structure within a month in Science,[5] which was two weeks before Klug's publishment in Nature on 3Å structure.[6] Klug complained to Francis Crick, who wrote the letters to A. Rich concerning the accusations.[7] However, Rich denied the scientific misconduct.[8]

Biographical information

  • Born 1937, South Korea
  • B.S.(1960), M.S.(1962) in chemistry, Seoul National University, South Korea
  • Ph.D(1966) University of Pittsburgh
  • Research Associate M.I.T. (1966-70) under A. Rich
  • Senior Research Scientist M.I.T. (1970-72) with A. Rich
  • Faculty of Biochemistry, Duke University School of Medicine (1972-78)
  • Professor, University of California, Berkeley (1978- )

References

  1. ^ a b Kim SH, Quigley GJ, Suddath FL, et al (1973). "Three-dimensional structure of yeast phenylalanine transfer RNA: folding of the polynucleotide chain". Science 179 (70): 285–8. PMID 4566654.
  2. ^ de Vos AM, Tong L, Milburn MV, et al (1988). "Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21". Science 239 (4842): 888–93. PMID 2448879.
  3. ^ Suddath FL, Quigley GJ, McPherson A, et al (1974). "Three-dimensional structure of yeast phenylalanine transfer RNA at 3.0angstroms resolution". Nature 248 (443): 20–4. PMID 4594440.
  4. ^ Clark BF (2001). "The crystallization and structural determination of tRNA". Trends Biochem. Sci. 26 (8): 511–4. Brian FC Clark's reminiscence on the tRNA structure pdf
  5. ^ Kim SH, Suddath FL, Quigley GJ, et al (1974). "Three-dimensional tertiary structure of yeast phenylalanine transfer RNA". Science 185 (149): 435–40. PMID 4601792.
  6. ^ Robertus JD, Ladner JE, Finch JT, et al (1974). "Structure of yeast phenylalanine tRNA at 3 A resolution". Nature 250 (467): 546–51. PMID 4602655.
  7. ^ Crick's first letter to A. Rich on the accusation, Jul 1974
  8. ^ Rich's reply to Crick's first letter, Aug 1974
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Kim_Sung-Hou". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE