Sialidase

Sialidase, accession number PF02973 is a widespread enzyme that catalyzes the hydrolysis of terminal acylneuraminic residues from oligosaccharides, glycolipids and glycoproteins. Also called neuraminidase.

Additional recommended knowledge

Essential Laboratory Skills Guide

Don't let static charges disrupt your weighing accuracy

How to quickly check pipettes?

It is present as a surface antigen in myxo viruses, hence sialidase inhibitors are used in anti-viral drugs.^[1]

Deficiency of this enzyme, an autosomal recessive trait, causes sialidosis; enzyme activity is also lacking in galactosialidosis. The EC nomenclature is exo-α-sialidase.

Genes

• NEU1, NEU2, NEU3, NEU4

References