Seronegative spondarthritis

"Seronegative" refers to the fact that these diseases are negative for Rheumatoid Factor and CCP in the serum.

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Seronegative spondyloarthritis is a group of diseases, including:

• psoriatic arthritis
• Reiter's disease
• arthritis in association with inflammatory bowel disease
• ankylosing spondylitis
• Behcet's syndrome
• Whipple's disease

These diseases has following conditions in common:

• They are in relation to HLA-B27
• sacroiliitis and spondylitis are present in them.
• familial aggregation occurs
• Overlap is likely in them
• rheumatoid factor is not present

References

• http://www.gpnotebook.co.uk/cache/-254803955.htm